Objectives
- Develop optimized viral vectors to facilitate the delivery of retinal gene therapies.
Results
- Creation of high-performance AAV vectors for retinal gene therapy.
- Acceleration of the discovery-to-application cycle thanks to structured data management and AI tools.
- Development of scalable and reproducible workflows for the design of gene therapy solutions in ophthalmology.
Issues
- Limited effectiveness of existing AAV vectors in targeting photoreceptors.
- Complex collaboration between researchers in experimental (wet lab) and computational (dry lab) laboratories.
- High costs and inefficiency of traditional AAV development approaches based on random designs.
ADLIN's role
- Deploy a collaborative workspace to structure and manage all multi-omics and analytics data.
- Ensure traceability and reproducibility of experimental and computational processes.
- Provide analytical tools and pipelines integrating wet lab and in silico approaches.
